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Anti Mullerian Hormone (AMH) or Mullerian inhibiting substance (MIS) is produced in small amounts by ovarian granulosa cells and becomes undetectable by menopause. It is known to inhibit recruitment of primordial follicles and decreases the responsiveness of growing follicles to FSH.
1 As a marker of ovarian reserve and responsiveness:
- Only marker decreasing continually during fertile life.
- Only marker not influenced by gonadotrophin feedback mechanism.
- Only marker stable during entire cycle.
- Best correlating marker with antral follicle count.
2.Prediction of outcome of assisted reproductive technology (ART). AMH concentration is related to the retrieved oocytes. The stability of AMH during the cycle and its predictive power, make it the most discriminating prognostic marker of ovarian response in ART.
3 Status of menopause.
4 Diagnosis and followup of granulose cell tumor ovary.
5 Evaluation of delayed or precocious puberty.
6 Differential diagnosis of impaired genetic development.
7 Diagnosis of Cryptorchidism and Anorchia.
8 Evaluation of gonadal function in men.
9 Diagnosis of PCOD.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.