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The blood test for lipase is ordered, often along with an amylase test, to help diagnose and monitor acute pancreatitis (inflammation of the pancreas), chronic pancreatitis, and other disorders that involve the pancreas. A lipase test may be ordered when a patient has symptoms of a pancreatic disorder, such as severe abdominal pain, fever, loss of appetite, or nausea. It may also be ordered at intervals when a doctor wants to monitor a patient with a pancreas condition to evaluate the effectiveness of treatment and to determine whether the lipase levels are increasing or decreasing over time.
In acute pancreatitis, Lipase increases within 4-8 hours, peaks at approximately 24 hours and decreases within 4-18 days. Lipase may also be elevated in chronic pancreatitis but if severe destruction of the acinar tissue has occurred; serum levels may be below those normally detected.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.