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Liver-Kidney Microsomal (LKM)
This test is used to detect LKM-1 antibodies which aids in the diagnosis of autoimmune hepatitis type 2 (AIH-2). LKM antibodies are markers of AIH-2 which usually begins in childhood and generally affects children younger than 18 years of age. LKM antibodies are associated with a more serious progression of the disease.
LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection. A significant deviation from the normal range may require further evaluation by your physician.
Anti LKM-2 antibodies are less frequently detected and are usually associated with Drug induced Hepatitis.
Anti LKM-3 antibodies are rarely detected and are usually associated with Autoimmune Hepatitis Type 2 (8-19%),Hepatitis c (6%) and Hepatitis D(6-13%).
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.