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RFT(Urea,Creatinine,Uric Acid, BUN)
Kidneys are vital organs that perform many functions to keep your blood clean and chemically balanced. Understanding how your kidneys work can help you to keep them healthy.
Kidneys are bean-shaped organs, each about the size of your fist. They are located near the middle of your back, just below the rib cage. The kidneys are sophisticated reprocessing machines. Every day, your kidneys process about 200 litres of blood to sift out about 2 litres of waste products and extra water. The waste and extra water become urine, which flows to your bladder through tubes called ureters. Your bladder stores urine until you go to the bathroom.
Your doctor may talk about the work your kidneys do as renal function. If you have two healthy kidneys, you have 100 percent of your renal function. This is more renal function than you really need. Some people are born with only one kidney, and these people are able to lead normal, healthy lives. Many people donate a kidney for transplantation to a family member or friend. Small declines in renal function may not cause a problem.
But many people with reduced renal function have a kidney disease that will get worse. You will have serious health problems if you have less than 25 percent of your renal function. If your renal function drops below 10 to 15 percent, you cannot live long without some form of renal replacement therapy either dialysis or transplantation.
Blood Urea Nitrogen (BUN)
A blood urea nitrogen (BUN) test measures the amount of nitrogen in your blood that comes from the waste product urea. Urea is made when protein is broken down in your body. Urea is made in the liver and passed out of your body in the urine.
A BUN test is done to see how well your kidneys are working. If your kidneys are not able to remove urea from the blood normally, your BUN level rises. Heart failure, dehydration, or a diet high in protein can also make your BUN level higher. Liver disease or damage can lower your BUN level. A low BUN level can occur normally in the second or third trimester of pregnancy.
Creatinine is a waste product in the blood created by the normal breakdown of muscle cells during activity. Healthy kidneys take creatinine out of the blood and put it into the urine to leave the body. When kidneys are not working well, creatinine builds up in the blood.
In the lab, your blood will be tested to see how many milligrams of creatinine are in one deciliter of blood (mg/dL).
Urea is produced when protein is broken down by the body. Healthy kidneys eliminate more than 90% of the urea the body produces, so blood levels indicate how well your kidneys are working.
The uric acid test is used to learn whether the body might be breaking down cells too quickly or not getting rid of uric acid quickly enough. The test also is used to monitor levels of uric acid when a patient has had chemotherapy or radiation treatments.
The uric acid test is ordered when a doctor suspects high levels of uric acid. Some patients with high levels of uric acid have a disease called gout, which is an inherited disorder that affects urine breakdown. Patients with gout suffer from joint pain, most often in their toes but in other joints as well. The test also is ordered as a monitoring test when a patient has undergone chemotherapy or radiation, to learn whether uric acid levels are getting dangerously high. The test may also be ordered if a patient appears to have failing kidneys. Patients who have high uric acid levels are sometimes put on a drug regimen to help lower uric acid levels.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.